Physician Views - Defining a suitable NASH therapy

Physician Views - Defining a suitable NASH therapy

Code: FW-20150301 | Published: Mar-2015 | Pages: - | FirstWord
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Excitement around the opportunity for therapies that are designed to treat nonalcoholic steatohepatitis (NASH) continues to grow and with little surprise.

Due to the lack of approved or satisfactory treatments, as well as the increasing prevalence of this disease, there remains high unmet in the treatment of NASH and therefore, high commercial potential for a successful NASH treatment. Currently there are several promising agents in Phase II trials that are being developed to address fat accumulation and inflammation in the liver, as well as potentially reverse the fibrosis caused by NASH.

A forthcoming NASH report by FirstWords Therapy Trends brand - to receive further details on this report click HERE -utilises interviews with 12 key opinion leaders (KOLs) to assess the current and future treatment landscape in NASH.








One concluding piece of analysis from this forthcoming report is a summary of the product characteristics for an ideal NASH therapy, as based on KOL feedback. This Physician Views poll uses that summary as inspiration and asks US and EU5-based gastroenterologists (taking into account the current treatment paradigm) to provide their feedback on the following product characteristics


A treatment for NASH should be orally administered once daily
- Not at all important
- Slightly important
- Moderately important
- Very important
- Extremely important

A treatment for NASH should be efficacious in resolving underlying NASH, as well as arresting or reversing fibrosis
- Not at all important
- Slightly important
- Moderately important
- Very important
- Extremely important

A treatment for NASH should have a direct or indirect effect on improving insulin sensitivity and cardiovascular risk profile
- Not at all important
- Slightly important
- Moderately important
- Very important
- Extremely important

A treatment for NASH should be safe and tolerable for long-term treatment, not interfere with other drugs the patient takes and not require use of additional drugs to counter side effects stemming from the NASH therapy
- Not at all important
- Slightly important
- Moderately important
- Very important
- Extremely important

A treatment for NASH should be moderately priced
- Not at all important
- Slightly important
- Moderately important
- Very important
- Extremely important



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